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New analysis finds that depression may not be caused by lower levels of serotinin in the brain.
A large scale study recently concluded which compared levels of serotonin and its breakdown products in the blood or brain fluids did not find a difference between people diagnosed with depression and healthy control (comparison) participants.
After decades of study, there remains no clear evidence that serotonin
levels or serotonin activity are responsible for depression, according
to a major review of prior research led by UCL scientists.
Interesting considering the US 224 million Selective serotonin reuptake inhibitors (SSRI) prescriptions.
the findings of this umbrella review are dependent on the quality of the included studies, and susceptible to their limitations. Most of the included studies were rated as low quality
I was on antidepressants for 5-6 years; they worked in so far as they took the edge off how shitty my life was at the time and made it bearable enough that the suicidal ideation stopped. Ultimately though my experience matched what the study found, external factors are a far bigger factor of depression than internal brain function.
Of course my brain wasn't producing serotonin for most of the time I was depressed; it was devoting all its resources to survival; I was barely making rent each month, under constant stress in toxic work environments and because of those two factors had no energy for any hobby or passion that could have given a sense of fulfillment.
Yess, exercise. Socializing. Sun. The obvious hurdle is to get people to this point in the first place.
Goretex_VidalUltimately though my experience matched what the study found, external factors are a far bigger factor of depression than internal brain function.
HiHowAreYouYess, exercise. Socializing. Sun. The obvious hurdle is to get people to this point in the first place.
It works for me tbh.
Just took an hour bike ride because i felt like shit, slept like shit, could barely get out of bed. Now i'm feeling fresh about to cook up some fresh chicken and brocolli then lift some fat weights tonight.
NeonGreenSharpieyeah it def helps but it is not a panacea
The sun, some push-ups, and some eggs are far closer to a panacea than arctarelizine, mirtzalipam and literal speed while also avoiding those pesky little side effects like weight gain, suicidal tendencies, mania, sexual dysfunction, etc. In addition they are completely free and don’t line Dr. lichbergs pocket with your money.
**This post was edited on Jul 27th 2022 at 2:54:08pm
mobadisThe sun, some push-ups, and some eggs are far closer to a panacea than arctarelizine, mirtzalipam and literal speed while also avoiding those pesky little side effects like weight gain, suicidal tendencies, mania, sexual dysfunction, etc. In addition they are completely free and don’t line Dr. lichbergs pocket with your money.
**This post was edited on Jul 27th 2022 at 2:54:08pm
Im not saying that medication is a miraculous cure, in fact there is none and medication alone isn't very effective. Sure physical activities, social support and life habits play a huge role in mental health, but everyone's different and there is no universal treatment. That's why if you are suffering from depression, the best way to deal with it is to seek help from a professional. Psychotherapy is probably the most effective treatment and pairing it with antidepressant can help in some cases.
**This post was edited on Jul 27th 2022 at 3:24:03pm
mobadisThe sun, some push-ups, and some eggs are far closer to a panacea than arctarelizine, mirtzalipam and literal speed while also avoiding those pesky little side effects like weight gain, suicidal tendencies, mania, sexual dysfunction, etc. In addition they are completely free and don’t line Dr. lichbergs pocket with your money.
**This post was edited on Jul 27th 2022 at 2:54:08pm
NeonGreenSharpieIm not saying that medication is a miraculous cure, in fact there is none and medication alone isn't very effective. Sure physical activities, social support and life habits play a huge role in mental health, but everyone's different and there is no universal treatment. That's why if you are suffering from depression, the best way to deal with it is to seek help from a professional. Psychotherapy is probably the most effective treatment and pairing it with antidepressant can help in some cases.
**This post was edited on Jul 27th 2022 at 3:24:03pm
Why the fuck would you pay someone to tell you you’re depressed when you already know that. On top of that say a little too much and next thing you know it you’re in the back of an ambulance strapped down hand and foot. Psychotherapy is pseudoscience at BEST.
mobadisWhy the fuck would you pay someone to tell you you’re depressed when you already know that. On top of that say a little too much and next thing you know it you’re in the back of an ambulance strapped down hand and foot. Psychotherapy is pseudoscience at BEST.
Depression may be solved by quality sleep, not too much and not to little. There is a J shaped curve which reflects optimal results and that peak lies at 8 hours of quality sleep. Sleep quality is not the same as sleep opportunity. Sleep opportunity is how much time you spent in bed "trying to sleep." Quality would start when you actually fall asleep, not just when you close your eyes.
I believe the vast majority of ADHD, depression, mood swings, and general feelings of "un-wellness" stem from inadequate sleep.
DTetzDepression may be solved by quality sleep, not too much and not to little. There is a J shaped curve which reflects optimal results and that peak lies at 8 hours of quality sleep. Sleep quality is not the same as sleep opportunity. Sleep opportunity is how much time you spent in bed "trying to sleep." Quality would start when you actually fall asleep, not just when you close your eyes.
I believe the vast majority of ADHD, depression, mood swings, and general feelings of "un-wellness" stem from inadequate sleep.
If we all just slept enough, drank enough water, abstained from drugs and alcohol, exercised regularly, and ate healthy we could eliminate a shit ton of diseases.
Buuuuuut fuck you I want my 20pc nuggets and they better have honey for dipping sauce or Imma lose my freaking mind.
DTetzDepression may be solved by quality sleep, not too much and not to little. There is a J shaped curve which reflects optimal results and that peak lies at 8 hours of quality sleep. Sleep quality is not the same as sleep opportunity. Sleep opportunity is how much time you spent in bed "trying to sleep." Quality would start when you actually fall asleep, not just when you close your eyes.
I believe the vast majority of ADHD, depression, mood swings, and general feelings of "un-wellness" stem from inadequate sleep.
I dunno why you're being downvoted so much cause sleep is 100% a major factor in mental health/ physical health. Its when the body can recharge/ revitalize itself through rest. People with atypical natural and unnatural sleep cycles tend to get punished when they're forced to conform to other ones. Getting enough rest/quality sleep isn't a "cure" so to speak but in terms of lessening symptoms/ effects, it can be some of the best medicine.
In my experience, mental health seems to be a combination of exercise, purpose, community, sleep, diet and discipline. Pills and therapy can absolutely help and some people need help defining their issues/ dealing with trauma and are a necessary step when categorizing the issue/thought patterns/ etc. At some point you'll have a plan where its necessary for the person to understand and want to put in the effort to get better while they hopefully have their needs met and support for when there are setbacks.
I feel like we've come to a crossroads in mental health where there's a recognition that the blame for can lie with structural and societal issues while at the same time its on the individual to make themselves better. Especially in America, individualism has lead to a degradation of community support which makes the deal feel even worse. Polarization politically makes it feel like you have to pick either society is at fault (goddamn libs whining) or that its the weak individual who can't pull themselves together (make america great again).
AndrewGravesSVI dunno why you're being downvoted so much cause sleep is 100% a major factor in mental health/ physical health. Its when the body can recharge/ revitalize itself through rest. People with atypical natural and unnatural sleep cycles tend to get punished when they're forced to conform to other ones. Getting enough rest/quality sleep isn't a "cure" so to speak but in terms of lessening symptoms/ effects, it can be some of the best medicine.
In my experience, mental health seems to be a combination of exercise, purpose, community, sleep, diet and discipline. Pills and therapy can absolutely help and some people need help defining their issues/ dealing with trauma and are a necessary step when categorizing the issue/thought patterns/ etc. At some point you'll have a plan where its necessary for the person to understand and want to put in the effort to get better while they hopefully have their needs met and support for when there are setbacks.
I feel like we've come to a crossroads in mental health where there's a recognition that the blame for can lie with structural and societal issues while at the same time its on the individual to make themselves better. Especially in America, individualism has lead to a degradation of community support which makes the deal feel even worse. Polarization politically makes it feel like you have to pick either society is at fault (goddamn libs whining) or that its the weak individual who can't pull themselves together (make america great again).
Serious things get downvoted on NS, most of the users are here to joke around. high% trolls
