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I've had a Macbook for about 5 years now and have never had a single issues with it. I've had iPods and an iPhone 4s and now a 5 since May, also with no issues. Until recently (really a couple of months). Again, this is the FIRST time I've ever had an issue with an Apple product since I got my 1st generation Shuffle.
My iPhone and iTunes won't sync. Any new music I add on my computer won't sync to my phone and vise versa. I couple of times I removed all my music and was able to add it again without any problems (just a pain in the neck). I went for it again tonight and now it won't sync.
I've searched all over the place for solutions and it seems like tons of people are having issues, but there aren't any solutions.