An electric guitar is as much not real music as a synthesizer. Why? They both rely on circuitry. Hendrix manipulated his guitar in ways that made extensive creative use of the circuitry in it and the amp, and that's how he got his sounds. What makes that different from a pianist playing a synthesizer with a sub bass sine wave and an LFO over it? Nothing. Synthesis is one of the most well-respected arts in music today, and it is also one of the most difficult. Not only do producers need to have an extensive knowledge of theory in order to do what they're doing, they are expected to create perfectly manufactured sounds, operating on certain frequency levels, using effects at different frequency levels, etc etc.... Its stupidly complicated, my piano training gave me a basis to work around for producing, and I use that knowledge and those skills every time I sit down at my computer, but I also need to learn loads about sound and its construction, which people that play "real instruments" don't need to know. I mean fuck, most bands hire a producer, an engineer, send their material off to get mastered.... Skrillex does all the above and he shreds guitar and is a competent vocalist.
Besides, people like you that say "oh it sounds like shit because its not from the 70s" are the same people that tried to put artists like Floyd, Hendrix, Dylan, etc down in the first place. You are career killers, and its an insult to the experimental, psychedelic, progressive nature of his music that you'd use his name and make such blatantly stupid statements. People like you turned the Beatles down. People like you turned Led Zeppelin down. Reconsider your musical opinions, if you want to be taken seriously.
And anyone that says "oh the scene is ruined now"... Its not about the stupid scene you fucking idiots, its about the music. Skrillex set out, took his own approach to his music, did what he wanted, and he is being rewarded extensively for it. And every producer out there that has done anything respects that, it just seems to be the people that haven't musically done shit or aren't trying to that hate on it. Taking drugs and partying =/= appreciating music.