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Profahoben_212No huge deal. Just dont tell the freshies that we are letting yall go to a different resort. Im alright with yall doing your thing, but i dont wanna deal with people skiing at like 6 different resorts and then being pissed because they cant ever ski with the team hahaha
NO REFUNDS FUCKERS
Don't worry, I got this. Who else is riding Northstar tho....?
Chubz.ON THE NEXT EPISODE OF THE PWOYM UNR TAKE OVER
will dkirse and Profahoben_212 ever stop taking over pwoym?
will erik transfer to UNR?
Is tahoe going to be overrun with extremely active NS'ers?
Profahoben_212Rahul and keinen for some reason refuse to get a squaw pass. But i think that is it. Not like they really did anything last year anyways hahahaha
Yeah I don't understand...both of them hella shred off piste so why get a Star pass? Lame. Plus Kienan only rides fatty's in the park so why not take the fattys to actual terrain?! Lol also I saw Rahul on campus today.
How hasnt the past many years of medical cannabis shown them the benefits in both rec and med form.
This is just getting ridiculous, fuck the DEA.
Once they realize how insanely profitable the weed game is (see: Colorado), theyll all be on board just like they are with booze. Same reason why cancer isnt cured: its more profitable to use chemo/radiation and have peoples families suffer and cures get rid of the money making aspect.
DeebieSkeebiesOnce they realize how insanely profitable the weed game is (see: Colorado), theyll all be on board just like they are with booze. Same reason why cancer isnt cured: its more profitable to use chemo/radiation and have peoples families suffer and cures get rid of the money making aspect.
Yeah its a bit fucked that families that dont wanna pay a fuck load for other treatments cant get it for their dying kid because the authorities think its not as safe as medicine that although it kills cancer, ruins the rest of your body.
Its just so they can profit because there are so fucking many unnecessary arrests for pot made. Millions of dollars are used for busting people with pot, in 2010 50% of the drug related arrests were for pot. Thats fucking stupid, here in NH our governor seems to feel that even decriminalization isnt smart yet, not even making a half ounce a $600 violation fine isnt enough, theyd still make money but Id be cool with it as a stoner cause I wont go to prison for possession of a magical plant. Were in the midst of a heroin epidemic she hasnt done shit about, I hear about more overdoses in NH than busts but they still seem to give a fuck about the most dangerous drug ever, marijuana.
I just dont get how A. they "dont" see meidcal benefits, B. the HUGE money in pot and C. jobs, so many people who smoke would love to work in a dispensary happily living life making a decent living and not working a shitty job then getting arrested for smoking pot from being stressed.
DeebieSkeebiesSame reason why cancer isnt cured: its more profitable to use chemo/radiation and have peoples families suffer and cures get rid of the money making aspect.
Ok I don't care about the medical marijuana bullshit, from what I can see there's no real evidence whatsoever and any non psychological/placebo mode of operation is completely unfeasible.
That said, this is the kind of garbage that does piss me off.
There will never, ever, be a cure for cancer, and it's not because big pharma is covering it up.
I would explain but PHD Comics does a match better job than I could ever do.
What I would add to it though, is recently we've made massive strides in the war against cancer. Survival rates are up, and recently immunotherapy has shown great promise, although it has been somewhat 'overhyped'.
*DUMBCAN*Ok I don't care about the medical marijuana bullshit, from what I can see there's no real evidence whatsoever and any non psychological/placebo mode of operation is completely unfeasible.
That said, this is the kind of garbage that does piss me off.
There will never, ever, be a cure for cancer, and it's not because big pharma is covering it up.
I would explain but PHD Comics does a match better job than I could ever do.
What I would add to it though, is recently we've made massive strides in the war against cancer. Survival rates are up, and recently immunotherapy has shown great promise, although it has been somewhat 'overhyped'.
This. There is no cure for cancer and there won't be for a very long time. It's not some conspiracy
*DUMBCAN*Ok I don't care about the medical marijuana bullshit, from what I can see there's no real evidence whatsoever and any non psychological/placebo mode of operation is completely unfeasible.
That said, this is the kind of garbage that does piss me off.
There will never, ever, be a cure for cancer, and it's not because big pharma is covering it up.
I would explain but PHD Comics does a match better job than I could ever do.
What I would add to it though, is recently we've made massive strides in the war against cancer. Survival rates are up, and recently immunotherapy has shown great promise, although it has been somewhat 'overhyped'.
I mean all I can argue with you is just the topic of pot. We know there virtually is no "cure for cancer" but CBD potent cannabis is what helps seriously ill patients, I wont say for sure but Im certain that CBDs will help eliminate some cancer cells (not entirely sure.)
That said, pretty much any other non bunko weed can "medicate" other people with illnesses, insomnia, depression etc. If a plant can cure someone and make them live a better life with no evidence of major long term affects, like the pills theyd be prescribed otherwise, I dont see why to shun medical marijuana aside from people lying about being sick to get a med card.......
*DUMBCAN*Ok I don't care about the medical marijuana bullshit, from what I can see there's no real evidence whatsoever and any non psychological/placebo mode of operation is completely unfeasible.
That said, this is the kind of garbage that does piss me off.
There will never, ever, be a cure for cancer, and it's not because big pharma is covering it up.
I would explain but PHD Comics does a match better job than I could ever do.
What I would add to it though, is recently we've made massive strides in the war against cancer. Survival rates are up, and recently immunotherapy has shown great promise, although it has been somewhat 'overhyped'.
What are you talking about? There are many known cures for cancers. And no, massive strides have not been made, cancer rates are way up compared to decades ago.
Titus69I mean all I can argue with you is just the topic of pot. We know there virtually is no "cure for cancer" but CBD potent cannabis is what helps seriously ill patients, I wont say for sure but Im certain that CBDs will help eliminate some cancer cells (not entirely sure.)
That said, pretty much any other non bunko weed can "medicate" other people with illnesses, insomnia, depression etc. If a plant can cure someone and make them live a better life with no evidence of major long term affects, like the pills theyd be prescribed otherwise, I dont see why to shun medical marijuana aside from people lying about being sick to get a med card.......
Medicinal disp just opened like 25 minutes away
It was proved in a major study that Cbd targets and kills cancer cells while leaving healthy cells intact.
Gods_FatherDon't forget it's the only plant in the entire world with all 10 essential amino acids plus efa's
ill talk to the DEA and tell them I will smoke all the weed theyve busted in the past month in 2-300 weeks and then they conduct tests on me to see how bad it really is. Id probably be asleep from the first few days still.
Gods_FatherWhat are you talking about? There are many known cures for cancers. And no, massive strides have not been made, cancer rates are way up compared to decades ago.
Get the fuck out of here. Cancer treatments, specifically immunotherapy treatments, are the BIGGEST discovery in a long time for cancer treatment. We currently have three major immune therapy checkpoint inhibitors on the market called Keytruda, Opdivo, and Yervoy with more down the line. Then further down the line we have CAR-T treatments from Juno and Kite among others, and then you have gene therapy from players like EDITAS and and Crispr.
Gods_FatherWhat are you talking about? There are many known cures for cancers. And no, massive strides have not been made, cancer rates are way up compared to decades ago.
.MASSHOLE.Get the fuck out of here. Cancer treatments, specifically immunotherapy treatments, are the BIGGEST discovery in a long time for cancer treatment. We currently have three major immune therapy checkpoint inhibitors on the market called Keytruda, Opdivo, and Yervoy with more down the line. Then further down the line we have CAR-T treatments from Juno and Kite among others, and then you have gene therapy from players like EDITAS and and Crispr.
^ what he said. The only reason we are seeing a rise in cancer is the fact that people are actually livin long enough to get cancer! Along with baby boomers hitting the prime ages for cancer, we are obvious going to see a rise in cancer rates.
Immunotherapy and gene therapy are the future for cancer treatments
Profahoben_212^ what he said. The only reason we are seeing a rise in cancer is the fact that people are actually livin long enough to get cancer! Along with baby boomers hitting the prime ages for cancer, we are obvious going to see a rise in cancer rates.
Immunotherapy and gene therapy are the future for cancer treatments
Yep.
There was actually a study somewhere, I need to find it. But basically it said if every one lives to be 125 years old we would all get cancer. Basically it's "when" you get cancer not an "if".
Maybe someone has read that article before. Don't quote me on anything I said cause it's been a while since I read it and I can't find it again.
The people that live in the town I work in have been complaining about feral cats shitting everywhere, getting into fights with dogs, and just generally causing trouble. So for the past few days my boss has been trapping them, then shooting them (Standard protocol). The body count this week was 4. We put them all in a trashbag and let it sit in the back of the shed until garbage day.
No big deal right? We put them in an airtight storage room. Then we double bagged it and sealed it with duct tape.
We were horribly wrong. Pretty much forgot about them all week. It got very hot this week. It was extremely humid and in the high 80s and low 90s. Trash day rolls around. We opened the door to the storage room. A swarm of flies exploded out of the room and became a cloud inside the rest of the shed. Then the smell crept in. 2 of my coworkers vomitted immediately. I followed soon after. Maggots had eaten their way through the trash bag and were covering part of the bag. We all threw up a few more times while getting it in the trashcan.
Titus69I mean all I can argue with you is just the topic of pot. We know there virtually is no "cure for cancer" but CBD potent cannabis is what helps seriously ill patients, I wont say for sure but Im certain that CBDs will help eliminate some cancer cells (not entirely sure.)
That said, pretty much any other non bunko weed can "medicate" other people with illnesses, insomnia, depression etc. If a plant can cure someone and make them live a better life with no evidence of major long term affects, like the pills theyd be prescribed otherwise, I dont see why to shun medical marijuana aside from people lying about being sick to get a med card.......
Medicinal disp just opened like 25 minutes away
Half (ok more than that) of my problem with medical marijuana is it seems like stoners trying to legitimise an addiction.
I won't believe that marijuana does anything more than provide psychological benefits for anything until I see the pharmacology, and I'll need that from a high impact factor journal.
That's not to say psychological benefits aren't useful. There's strong anecdotal that marijuana can alleviate side effects of chemo, which is a definite benefit. Same with several other diseases. Psychology is incredibly important when it comes to fighting serious diseases. People with fewer side effects are happier, and happier people live longer, even in the face of death.
So basically, I'm for medical marijuana, but I'm not going to pretend that there are any significant medical benefits.
Gods_FatherWhat are you talking about? There are many known cures for cancers. And no, massive strides have not been made, cancer rates are way up compared to decades ago.
Thank you for telling me of this, I won't bother going in to work tomorrow. Suppose there's no need for molecular oncology researchers now I've been told there are loads of 'cures for cancers'.
/s (if that was needed).
Cancer survival rates have significantly improved in the past decades. Obvious leaps we've made include the development of cis-platin derivative drugs that avoid tumour resistance, this is largely possible due to fairly recent improvements in our knowledge of DNA replication in cancer cells.
Far more recently we've developed immunotherapy, which has gained quite a lot of public attention, or at least the positive studies have.
In my lab we have designed methods to specifically intercalate* tumour cell DNA with fluorescent rhodium complexes, allowing us to image cell replication in ways we haven't been able to before. This is just one attempt to analyse a problem, that could lead to a solution of another problem, that could help us understand another problem, that might remove a stone from the metaphorical mountain that is 'the cancer problem'. But that's modern science, there are few moments of inspiration leading to major breakthroughs, but hopefully the combined efforts of thousands of researchers will make progress.
That is why I'm skeptical when some stoner says "yeah man, I know you got cancer but all this scientific medicine bullshit just kills you, you should smoke this magic herb instead."
It's like homeopathy 2.0.
*We slot a wide and flat molecule between two DNA base pairs.
Gods_FatherIt was proved in a major study that Cbd targets and kills cancer cells while leaving healthy cells intact.
*DUMBCAN*Half (ok more than that) of my problem with medical marijuana is it seems like stoners trying to legitimise an addiction.
I won't believe that marijuana does anything more than provide psychological benefits for anything until I see the pharmacology, and I'll need that from a high impact factor journal.
That's not to say psychological benefits aren't useful. There's strong anecdotal that marijuana can alleviate side effects of chemo, which is a definite benefit. Same with several other diseases. Psychology is incredibly important when it comes to fighting serious diseases. People with fewer side effects are happier, and happier people live longer, even in the face of death.
So basically, I'm for medical marijuana, but I'm not going to pretend that there are any significant medical benefits.
Thank you for telling me of this, I won't bother going in to work tomorrow. Suppose there's no need for molecular oncology researchers now I've been told there are loads of 'cures for cancers'.
/s (if that was needed).
Cancer survival rates have significantly improved in the past decades. Obvious leaps we've made include the development of cis-platin derivative drugs that avoid tumour resistance, this is largely possible due to fairly recent improvements in our knowledge of DNA replication in cancer cells.
Far more recently we've developed immunotherapy, which has gained quite a lot of public attention, or at least the positive studies have.
In my lab we have designed methods to specifically intercalate* tumour cell DNA with fluorescent rhodium complexes, allowing us to image cell replication in ways we haven't been able to before. This is just one attempt to analyse a problem, that could lead to a solution of another problem, that could help us understand another problem, that might remove a stone from the metaphorical mountain that is 'the cancer problem'. But that's modern science, there are few moments of inspiration leading to major breakthroughs, but hopefully the combined efforts of thousands of researchers will make progress.
That is why I'm skeptical when some stoner says "yeah man, I know you got cancer but all this scientific medicine bullshit just kills you, you should smoke this magic herb instead."
It's like homeopathy 2.0.
*We slot a wide and flat molecule between two DNA base pairs.
Show me.
Curious, do you believe possessing cannabis should be illegal? There aren't significant medical benefits of cannabis? Hahahahaha! It's the only plant with all 10 essential amino acids. What's our body equipped with cannabis receptors for?
Are you saying there aren't any known cures for cancer? Cause I can think of too many to list lol...
It's too bad you see all cannabis users as addicted smokers, guess you've never heard of vegetables before.
hahahaha do a quick Google search if you want to read the study, goof expecting me to do that for you hah.
Gods_FatherAs if only old people are getting cancer haha.
Yeah you're a fucking idiot.
No old people are not the only people to get cancer....but it does become the leading cause of death of people age 40 plus. So not sure what your argument is? Stop talking about shit you don't know about. You look like an ass
No old people are not the only people to get cancer....but it does become the leading cause of death of people age 40 plus. So not sure what your argument is?
And it was not even close to the leading cause of death decades ago...
Gods_FatherCurious, do you believe possessing cannabis should be illegal? There aren't significant medical benefits of cannabis? Hahahahaha! It's the only plant with all 10 essential amino acids. What's our body equipped with cannabis receptors for?
Are you saying there aren't any known cures for cancer? Cause I can think of too many to list lol...
It's too bad you see all cannabis users as addicted smokers, guess you've never heard of vegetables before.
hahahaha do a quick Google search if you want to read the study, goof expecting me to do that for you hah.
No, I'm totally for the decriminalization of all drugs, although I'm against the legitimisation of addiction. That includes cigs, alcohol, cocaine, weed, glue, video games, whatever really. Nothing good comes from addictions or dependencies.
I'm disappointed in myself, I had to google how many amino acids there were, but I suppose the actual count is kinda irrelevant. Problems that come from spending a lot of time working with unnatural amino acids.
There are 20 essential amino acids, and you find them everywhere. They don't survive combustion, so when you smoke weed you don't take them in.
Our body has cannabinoid receptors because our body uses endocannabinoids as signalling molecules. This doesn't mean ingesting THC is a good thing.
List some of your 'cures for cancer' and I'll tell you why they don't work. (hint: it's because they don't exist)
*DUMBCAN*No, I'm totally for the decriminalization of all drugs, although I'm against the legitimisation of addiction. That includes cigs, alcohol, cocaine, weed, glue, video games, whatever really. Nothing good comes from addictions or dependencies.
I'm disappointed in myself, I had to google how many amino acids there were, but I suppose the actual count is kinda irrelevant. Problems that come from spending a lot of time working with unnatural amino acids.
There are 20 essential amino acids, and you find them everywhere. They don't survive combustion, so when you smoke weed you don't take them in.
Our body has cannabinoid receptors because our body uses endocannabinoids as signalling molecules. This doesn't mean ingesting THC is a good thing.
List some of your 'cures for cancer' and I'll tell you why they don't work. (hint: it's because they don't exist)
That's interesting...you don't think having an addiction to something like skiing or golf should be legal?
You don't just smoke cannabis for health benefits, you eat, drink or apply it. Thc is a strong pain reliever, an appetite stimulant and a study concluded that even smoking cannabis can alleviate asthma attacks.
a few are cannabis/cannabis oil, reishi mushrooms, turmeric, frankincense, vitamin c(not really sure how you can claim they don't work when there are countless cases of people curing their cancer with food)
Gods_FatherAnd it was not even close to the leading cause of death decades ago...
Man, you are really an idiot.
Cancer rates have gone up for two main reasons-life span increase and lifestyle changes.
Life spans have risen for decades, and as a result, we are seeing older generations. If you took a basic biology course you would know our cells contain DNA and within this DNA are mistakes. As we age, our cells divide and these mistakes are more likely to occur, which is why you see more cancer in older people. That being said, some people just get unlucky and have a cellular mutation or genetic predisposition for certain mutations, for example, p53 mutations in women.
However, now with our medical technology we can catch these genetic issues with recent medical technology involving gene sequencing.
Lifestyle changes involve higher obesity rates, more red meat, sunbathing/tanning beds, and frankly smoking and alcohol.
But you know what the amazing thing is, cancer survival rates have gone up too thanks to modern medicine. Having cancer is no longer a death sentence. There are some out there, like pancreatic cancer, that are still difficult to treat, but many other cancers are now treatable and survivable.
My grandmother was diagnosed with breast cancer at the young age of 53. She managed to hold it in remission until she was 70, and then was able to contain until the ripe old age of 88, when she eventually lost the battle.
Cancer rates have gone up for two main reasons-life span increase and lifestyle changes.
Life spans have risen for decades, and as a result, we are seeing older generations. If you took a basic biology course you would know our cells contain DNA and within this DNA are mistakes. As we age, our cells divide and these mistakes are more likely to occur, which is why you see more cancer in older people. That being said, some people just get unlucky and have a cellular mutation or genetic predisposition for certain mutations, for example, p53 mutations in women.
However, now with our medical technology we can catch these genetic issues with recent medical technology involving gene sequencing.
Lifestyle changes involve higher obesity rates, more red meat, sunbathing/tanning beds, and frankly smoking and alcohol.
But you know what the amazing thing is, cancer survival rates have gone up too thanks to modern medicine. Having cancer is no longer a death sentence. There are some out there, like pancreatic cancer, that are still difficult to treat, but many other cancers are now treatable and survivable.
My grandmother was diagnosed with breast cancer at the young age of 53. She managed to hold it in remission until she was 70, and then was able to contain until the ripe old age of 88, when she eventually lost the battle.
Sorry, but people in the 70s ate lots of red meat(more than today according to a usda chart I just read) and they drank, smoked(prob even more prevalently than today) and statistically lived similarly long lives as people today. No cancer though. From your rant you're making it sound like I don't agree with any modern medicine lol? I'm not a fan of chemo though, something that is even defined as killing you.
Gods_Father.....so in the 60s and 70s people weren't commonly living to age 50? Weird, who told you that?
.MASSHOLE.Man, you are really an idiot.
Cancer rates have gone up for two main reasons-life span increase and lifestyle changes.
Life spans have risen for decades, and as a result, we are seeing older generations. If you took a basic biology course you would know our cells contain DNA and within this DNA are mistakes. As we age, our cells divide and these mistakes are more likely to occur, which is why you see more cancer in older people. That being said, some people just get unlucky and have a cellular mutation or genetic predisposition for certain mutations, for example, p53 mutations in women.
However, now with our medical technology we can catch these genetic issues with recent medical technology involving gene sequencing.
Lifestyle changes involve higher obesity rates, more red meat, sunbathing/tanning beds, and frankly smoking and alcohol.
But you know what the amazing thing is, cancer survival rates have gone up too thanks to modern medicine. Having cancer is no longer a death sentence. There are some out there, like pancreatic cancer, that are still difficult to treat, but many other cancers are now treatable and survivable.
My grandmother was diagnosed with breast cancer at the young age of 53. She managed to hold it in remission until she was 70, and then was able to contain until the ripe old age of 88, when she eventually lost the battle.
Pretty much what he said...once again.
Also people were living much shorter lives. Lifespans are up almost 15 years since the 50s. Expected age of death at birth in the 30s was the mid 50s.
People werent dying from these chronic diseases, they were weakened by them and pneumonia/flu/whatever other preventable disease took them. It wasnt until the widespread use of vaccines and antibiotics that people were commonly able to live through those and actually die from chronic disease.
Gods_FatherSorry, but people in the 70s ate lots of red meat(more than today according to a usda chart I just read) and they drank, smoked(prob even more prevalently than today) and statistically lived similarly long lives as people today. No cancer though. From your rant you're making it sound like I don't agree with any modern medicine lol? I'm not a fan of chemo though, something that is even defined as killing you.
Weird how middle age people in the 70s have been the ones dying of cancer for the last decade or so. They smoked a hell of a lot more than people today....weird how they are commonly dying from lung/heart cancer for the last few decades. Thanks for once again proving our point
Gods_FatherSorry, but people in the 70s ate lots of red meat(more than today according to a usda chart I just read) and they drank, smoked(prob even more prevalently than today) and statistically lived similarly long lives as people today. No cancer though. From your rant you're making it sound like I don't agree with any modern medicine lol? I'm not a fan of chemo though, something that is even defined as killing you.
Right, born in the 50s/60s, currently 50-70, the prime age for cancer. Hence the lifestyle choices.
Chemo? You don't like chemo? What the fuck do you want these people to do? Chemo is a 1st line drug BECAUSE it has been proven effective along side surgery and radiation. Thankfully, as gene sequencing progresses and we begin to find "personalized" medicine treatments (like those for PD-1/PD-L1, HER2, BCR-ABL, etc) that can be used as first-line as well. But those medicines are not effective unless those biomarkers are there, hence why chemo is, and always will be, necessary.
Do you know ANYTHING about cancer treatment? You have 1st line treatments like a paclitaxel which are proven most effective, sometimes against a wide range of cancers, then 2nd line (like Opdivo/Yervoy/Keytruda depending on the cancer) which are cancer treatments that are given when 1st line either stops working or is not effective enough, and then 3rd and 4th line which normally are given to extend life, not cure.
If you read any drug trial you would understand why there is a variety of endpoints such as Overall Survival Rate, Progression-Free Survival, Objective Response Rate, Time to Progression, Time to Treatment Failure, etc.
Gods_Father"so in the 60s and 70s people weren't commonly living to age 50? Weird, who told you that?"
Don't get me wrong, increased life expectancy does increase cancer rates, I just think there are more factors.
THere are thousands of factors. Nothing you can do will stop you from getting cancer. You can not touch a carcinogen in your life and your genes could still fuck up and you get cancer. Luck of the draw really...sucks
.MASSHOLE.Right, born in the 50s/60s, currently 50-70, the prime age for cancer. Hence the lifestyle choices.
Chemo? You don't like chemo? What the fuck do you want these people to do? Chemo is a 1st line drug BECAUSE it has been proven effective along side surgery and radiation. Thankfully, as gene sequencing progresses and we begin to find "personalized" medicine treatments (like those for PD-1/PD-L1, HER2, BCR-ABL, etc) that can be used as first-line as well. But those medicines are not effective unless those biomarkers are there, hence why chemo is, and always will be, necessary.
Do you know ANYTHING about cancer treatment? You have 1st line treatments like a paclitaxel which are proven most effective, sometimes against a wide range of cancers, then 2nd line (like Opdivo/Yervoy/Keytruda depending on the cancer) which are cancer treatments that are given when 1st line either stops working or is not effective enough, and then 3rd and 4th line which normally are given to extend life, not cure.
If you read any drug trial you would understand why there is a variety of endpoints such as Overall Survival Rate, Progression-Free Survival, Objective Response Rate, Time to Progression, Time to Treatment Failure, etc.
Why are there so many cases of people who have opted out of chemo and have been able to cure their cancer? Even people who were given months or weeks to live.
Gods_FatherWhy are there so many cases of people who have opted out of chemo and have been able to cure their cancer? Even people who were given months or weeks to live.
What was their cancer type? What was their treatment? You don't need chemo as I have stated, you have other options IF your cancer expresses certain receptors.
More importantly, what percentage of patients survived without chemo compared to those who survived with it?
