Replying to Cleanin up the comp. - need some help

k i have a ton of stuff on my harddrive, way too much its almost full, ive uninstalled most of my games and stuff but its not doing a whole lot. so i think i got some spyware or something but i dunno - ive checked using microsoft anti-spyware AND spybot search and destroy and deleted everything it found. also morpheus stopped working and it wont let me uninstall it (ill go to add/remove programs and click uninstall but the window closes imediatly after it opens so i cant do anything with it). is there a way to wipe everything back to manufacturer settings - like what programs you bought it with. or even better a program that allows you what to choose, i got a ton of music and i'd rather not go through the hassle of putting it onto CDs and then putting them back on the comp. after i clean it.